This study used quantitative remote sensing method, in combination with RUSLE model, and GIS software, utilizing a series of data such as digital elevation model (DEM), rainfall and soil properties, the characteristics of spatial-temporal differentiation of soil erosion of Zuli river basin from 1995 to 2015 was estimated. By analysis of the temporal variation of the erosion modulus, temporal variation of erosion intensity and spatial pattern of erosion intensity, the results of this research were summed as follows: The erosion modulus was 2 877.87 t/(km2·a）in 1995, 3 372.24 t/(km2·a） in 2005, and 3 713.23 t/(km2·a） in 2015, respectively, suggesting the increasing erosion rates. In the case of the spatial pattern of soil erosion, the erosion modulus was high value on the high side place in the middle of the study area and low value in the south and north. Besides, the soil erosion mounts was high on the side in the mountains and low near the river valley. Four types of simulation were proposed according to the characteristics of study area. The results showed that the efficient governance model (EGM) was the best governance model area, which could effectively control soil loss, the average modulus properties was 2 656. t/(km2·a）.