The natural condition of Tibet-Qing Plateau is unique but especially fragile. Thus, the potential hazards of soil loss may be greater than other place. Under the background of global change and West Development Strategy, the research on the soil loss on Tibet-Qing Plateau is of great importance. According to its natural condition, three main characters were summarized: diversity in erosion type, unevenly-distributed erosion intensity, weakness but great potential hazards in man-made erosion. Analyzed the temporal and spatial distribution of soil loss with the sediment yield date of river. It was showed that the distribution of the sediment modulus was greatly uneven and was mainly determined by rainfall and land cover. To a certain extent, the soil erosion intensity could be demonstrated by the sediment modulus. The sediment yield was highly concentrated in July and August, accounting for 65%. Due to the thaw of snow and ice in early summer, the peaks of runoff and sediment yield could precede that of rainfall.