To study the effects of different cultivation methods and irrigation schedules on growth, yield, and water use of winter wheat, three cultivation modes were conducted with field experiment in Shandong province:Traditional Cultivation (TC), Ridge Cultivation (RC), and High and Low Cultivation (HLC), three levels of irrigation quota (900 m³/hm², 720 m³/hm², 540 m³/hm²) were set up in RC and HLC respectively, while there was only 900 m³/hm² irrigation quota for TC. The changes in soil moisture, water consumption, and water use efficiency (WUE) of winter wheat in the three cultivation methods were studied. The results showed:the soil water content of winter wheat at different growth stages was significantly different under different cultivation methods, and the ability of storing rainfall in RC method was better than the other two methods. The cultivation methods had significant effects on the water consumption characteristics and water use efficiency of winter wheat, and there was a significant positive correlation between winter wheat yield and water consumption (R²=0.86, P<0.01). Compared with RC and TC, the wheat of HLC developed vigorously, with higher number of panicles and grains per mu. The total water consumption under HLC method was 14.16% and 19.90% higher than that of TC and RC respectively, while the yield of HLC was 22.63% and 27.37% higher than that of TC and RC respectively. Furthermore, the WUE of HLC was 7.69% and 6.87% higher than that of TC and RC. Overall, HLC cultivation can significantly improve the yield and WUE of winter wheat, and it could be an ideal water-saving and high-yield cultivation method in the study area.