Moderately salinized sunflower field in Hetao Irrigation District were used to explore the effects of moistube-irrigation on the changes of soil water and salt distribution and crop yield to support the generalization and application of moistube-irrigation technology. Two soil buried depths (10, 20 cm) and four irrigation quotas (Full irrigation:T1, T5, mild water shortage:T2, T6, moderate water shortage:T3, T7, severe water shortage:T4, T8) were set up to study the changes of soil water and salt distribution and sunflower yield and water use efficiency (WUE). The results showed that in the same depth of moistube, as the irrigation quotas increased, the soil moisture was the higher and soil salinity was lower. The buried depth of moistube was an important factor affecting the distribution of soil water and salt. In the same irrigation quota, compared with the buried depth of 20 cm, The soil moisture contents with the buried depth of 10 cm was larger in 20-30 cm, the coefficient of variation of soil water content was less in 10-60 cm, and the salt content was significantly reduced. Under the condition of full irrigation and moistube buried depth of 20 cm, it was beneficial to inhibit the accumulation of soil salt in the root zone of sunflower. After the ripening of sunflower in 2015, the average relative salt accumulation rate of 0-60 cm treated by T1 was 9.3%, which was respectively lower than those of T2 and T5 treatment by 53.3% and 45.9% respectively. After the ripening of sunflower in 2016, the soil of 0-60 cm showed desalting and the amount of desalination decreased with the decrease of irrigation quotas, and increased with the increase of buried depth. At the same burial depth, the yield gradually increased with the increase of irrigation water volume. Under the same irrigation quota, moistube with buried depth of 20 cm had an increasing trend and the difference was significant compared with the depth of 10 cm. In summary, in the case of sufficient irrigation and moistube buried depth of 20 cm, the soil salt accumulation rate of 0-60 cm was 9.3%, and the crop yield was the highest, and the WUE was higher. It is recommended that the moistube buried depth of 20 cm and sufficient irrigation should be carried out in the sunflower field, and the soil should be leached by autumn flooding to decrease salt of surface layer in the Hetao area. This study provides a reference for the application of moistube-irrigation in moderately salinized areas.