In order to investigate the effects of rainfall intensity and vegetation coverage on the runoff and sediment yield on granite red soil slope, this study analyzed regularity of runoff and sediment yield and their correlation under different rainfall intensities (0.5, 1.0, 1.5 mm/min) and vegetation coverages (0, 20%, 40%, 60%) through indoor artificial simulated rainfall test. The results showed that:(1) Under the same rainfall intensity, the initial flow time was delayed with the increasing of vegetation coverage, and it was advanced with the increasing of rainfall intensity. The greater the rainfall intensity, the earlier the flow time was. (2) The runoff rate and erosion rate of each slope decreased with the increasing of vegetation coverage, and the higher the vegetation coverage was, the smaller the fluctuation range of runoff rate and erosion rate was, and the more stable the erosion process was. (3) On the slope covered by vegetation, the sediment was mainly water-stable aggregates less than 0.25 mm. The proportion of water-stable aggregates greater than 0.25 mm in the sediment increased with the increasing of rainfall intensity, and the increase range decreased with the increasing of vegetation coverage. (4) Vegetation coverage and rainfall intensity were significantly correlated with runoff generation time, runoff rate and erosion rate (P<0.01). The correlation between slope runoff generation process and rainfall intensity was greater than that between slope runoff generation process and vegetation cover change. The correlation between slope sediment yield and vegetation cover change was greater than that between slope sediment yield and rain intensity change. The relationship between cumulative runoff and cumulative sediment yield on vegetation covered slope was in consistent with power function model(R²>0.98)under different rainfall intensities. The results could provide a scientific reference for soil erosion control and ecological restoration in red soil hilly area of southern China.