Abstract:The field experiments of two consecutive years were conducted with randomized block design with six treatments:spraying water (CK), spraying Bordeaux Mixture (BDM), spraying Kocide 2000 (KCD), spraying copper-based nutritional foliar fertilizer (CF), spraying iron-copper-based nutritional foliar fertilizer (CFFe) and spraying zinc-boron-copper-based nutritional foliar fertilizer (CFZnB), respectively. The effects on yield and quality, chlorophyll content and various indicators of photosynthetic characteristics of leaves, the plant and fruit total contents and accumulations of Cu, Zn and Fe, disease index of pepper and enzyme activities of soil were determined. The results showed that the CFFe, CFZnB, CF, and KCD significantly increased the photosynthetic rate, stomatal conductance, transpiration rate, and the chlorophyll content, in which the maximum increment was 20.13% by CFFe and followed by CFZnB that increased by 16.19%~18.13% as compared to the CK and significantly decreased intercellular CO2 concentration in pepper leaves. The BDM, KCD, CF, CFFe and CFZnB significantly increased the plant and fruit total contents and accumulations of Cu. The CFZnB, CFFe, CF, and KCD significantly increased the plant and fruit total contents and accumulations of Zn. The CFFe, CFZnB, CF and KCD significantly increased the plant and fruit total contents and accumulations of Fe. The CFFe, CFZnB, CF, KCD and BDM greatly reduced the disease index at the early fruiting and full fruiting periods of pepper. Soil urease activities of the CFFe and CFZnB were the highest. All treatments and CK significantly increased the soil catalase activities as compared to the BDM. The CFFe, CFZnB, CF, and KCD significantly increased the soil sucrase activities as compared to the CK. Pepper nutritional quality of CFFe was the best and followed by the CFZnB. The CFFe, CFZnB, CF, and KCD significantly increased the yield of pepper, with the CFFe maximally increased by 13.22% and followed by the CFZnB that increased by 11.93%~12.52% as compared to CK. The CFFe, CFZnB, and CF significantly increased the yield of pepper, the CFFe was the most and followed by the CFZnB. The CFFe, CFZnB, and CF significantly improved the quality of pepper, pepper nutritional quality of CFFe was the best, the second was the CFZnB. Copper-based nutritional foliar fertilizer developed by Shandong Agricultural University, as a kind of bactericidal and plant nutrition health care double functional foliar fertilizer, can significantly increase yield and improve the quality of pepper, and has certain effect on prevention and control of pepper disease. Therefore, iron-copper-based nutritional foliar fertilizer and zinc-boron-copper-based nutritional foliar fertilizer are recommended.