From April 15 to October 15 in 2015, a field experiment was carried out to explore the appropriate water and fertilizer management mode in the farming area of black soil in Northeast China. In this paper, the effects of mulching, fertilizer amount and fertilization model on water consumption, maize biological characters, water use efficiency (WUE) and partial fertilizer productivity were studied. The experiment consist of two mulching treatments, i.e. mulching (M) and no-mulching (W), 3 fertilization levels with 230 kg N/hm2 (W1), 280 kg N/hm2 (W2) and 330 kg N/hm2 (W3), and 3 fertilization schemes of 60%-40%-0% (F1), 60%-20%-20% (F2), 33%-33%-33% (F3), a total of 20 treatments. Results showed that the film mulching treatments reduced the ineffective evaporation of soil moisture. Plant grew much better with the increase of fertilizer amount, then the demand for soil moisture increased, and the maximum soil moisture consumption treatment was WW3F2. Moreover, the differences of fertilizer amount and fertilization scheme result in different biological characters and plant yield. Soil nutrient use efficiency increased with increasing fertilizer amount under F2 treatment, specifically, plant yield of MW3F2 increased by 2.8% and 12.7% compared with MW3F1 and MW3F3, respectively. Finally, heavy fertilization and water consumption could increase the yield, while decreased WUE and fertilizer partial productivity, and also f MW1F2 and MW3F2 were the priority of planting pattern in black soil area.