Soil enzymatic activities and its relationship with available heavy metal content in rhizosphere of hyperaccumulator Sedum alfredii Hance were studied based on field investigation and pot experiment.The results showed that DTPA extractable-Zn content in rhizosphere soil of Sedum alfredii Hance decreased by 14.3%,7.9% and 47.4%,and DTPA extractable-Cd content decreased by 25.1%,21.9% and 20% as compared with non-rhizosphere soil,when planted in mining,heavy polluted soil and light polluted soil,respectively.In Pb/Zn mining area where hyperaccumulating ecotype Sedum alfredii grow,sucrase,acid phosphatase and dehydrogenase activity in soil were much higher than other place.Soil enzymatic activities(urease,acid phosphatase and dehydrogenase) in rhizosphere of hyperaccumulating ecotype Sedum alfredii were much higher than both in non-rhizosphere and rhizosphere of non-hyperaccumulating ecotype,especially in mining and heavy polluted soil.Urease,sucrase and dehydrogenase activities in rhizosphere of hyperaccumulating ecotype Sedum alfredii were restrained by Pb,Zn,Cd and Cu significantly,whereas acid phosphatase activitie was prompted by Pb.Acid phosphatase and dehydrogenase activity was significantly correlated with combined available content of soil heavy metals in rhizosphere of hyperaccumulator Sedum alfredii Hance.